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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR3C1
All Species:
8.18
Human Site:
S141
Identified Species:
20
UniProt:
P04150
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04150
NP_000167.1
777
85659
S141
S
V
P
E
N
P
K
S
S
A
S
T
A
V
S
Chimpanzee
Pan troglodytes
A7X8B3
933
98902
A181
D
S
S
G
T
A
A
A
H
K
V
L
P
R
G
Rhesus Macaque
Macaca mulatta
XP_001097126
777
85480
S141
S
V
P
E
N
P
K
S
S
A
S
T
A
V
S
Dog
Lupus familis
XP_535225
780
85853
S145
E
N
P
K
S
S
V
S
A
V
S
A
A
P
T
Cat
Felis silvestris
Mouse
Mus musculus
P06537
783
86034
K149
T
S
R
P
E
N
P
K
S
S
T
P
A
A
G
Rat
Rattus norvegicus
P06536
795
87538
K161
T
S
V
P
E
N
P
K
S
S
T
S
A
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510749
775
84527
P140
L
N
K
S
S
G
V
P
E
S
S
K
G
P
A
Chicken
Gallus gallus
P07812
786
85725
G140
E
Q
K
A
V
D
A
G
P
G
A
P
G
P
S
Frog
Xenopus laevis
P49844
776
84959
S142
I
A
N
L
Q
A
K
S
L
A
P
D
K
L
I
Zebra Danio
Brachydanio rerio
NP_001018547
746
81903
F140
G
G
V
D
P
N
L
F
P
L
K
T
E
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.3
98.3
93
N.A.
89.5
88.4
N.A.
82.6
34.4
63.3
48.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
47.7
98.9
96.2
N.A.
93.7
92
N.A.
90.2
47.8
77.3
64.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
26.6
N.A.
13.3
13.3
N.A.
6.6
6.6
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
53.3
N.A.
33.3
40
N.A.
26.6
13.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
20
20
10
10
30
10
10
50
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
10
0
0
0
0
0
10
0
10
0
% D
% Glu:
20
0
0
20
20
0
0
0
10
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% F
% Gly:
10
10
0
10
0
10
0
10
0
10
0
0
20
0
30
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
20
10
0
0
30
20
0
10
10
10
10
0
0
% K
% Leu:
10
0
0
10
0
0
10
0
10
10
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
10
0
20
30
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
30
20
10
20
20
10
20
0
10
20
10
30
0
% P
% Gln:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
20
30
10
10
20
10
0
40
40
30
40
10
0
0
30
% S
% Thr:
20
0
0
0
10
0
0
0
0
0
20
30
0
10
10
% T
% Val:
0
20
20
0
10
0
20
0
0
10
10
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _